Human insulin receptor 83-14 (alpha chain) monoclonal antibody

Human insulin receptor antibody 83-14 is a mouse monoclonal antibody (IgG2_a) that recognizes an epitope within amino acids 469-572 in the extracellular domain of the human insulin receptor. The antibody was prepared by immunising mice with a preparation of IM9 lymphocytes and then with purified insulin receptor. The antibody strongly inhibits the binding of insulin to the insulin receptor in 3T3 cells.