Human Pro IGF-I EA (92 – 105) antiserum (Rabbit)

Human ProIGF-I EA (92-105) antiserum was prepared by immunising rabbits with a 15 amino acid peptide derived from the E domain of human ProIGF-I EA linked to diphtheria toxoid. The peptide is located at the C terminus of the 153 amino acid ProIGF-I EA derived from alternative splicing of the human igf-1 gene. The antiserum recognises ProIGF-I EA but not ProIGF-I EB, ProIGF-I EC, mature IGF-I or IGF-II. Sequence analysis suggest it is likely to recognise ProIGF-I EA related proteins in a range of other species including non-human primates, rabbit, guinea-pig, dog, horse, sheep and goat but not rodents, due to alternative splicing of the igf-1 gene.