Human Pro-IGF-IIE (138 – 156) antiserum (Rabbit)

Human ProIGF-II E (138-156) antiserum was prepared by immunising rabbits with a 19 amino acid peptide derived from C terminus of the E domain of human IGF-II E linked to diphtheria toxoid. As a consequence, the antiserum recognises full length IGF-II E derived from alternative splicing of the human igf-2 gene before proteolytic cleavage occurs. It does not recognise mature IGF-II or IGF-I. Sequence analysis suggests it is likely to recognise IGF-II E proteins in non-human primates but not other species.