Human [Leu60] IGF-I

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Product description

100 µg
Product code

Human [Leu60] insulin-like Growth Factor-I ([Leu60] IGF-I) is an analogue of human IGF-I which has a Leucine substitution in place of Tyrosine at position 60 of the human IGF-I sequence. [Leu60]IGF-I has normal binding to acid-stripped human serum binding proteins but has reduced binding to the type 1 IGF receptor and to the insulin receptor compared to IGF-I. It is a useful analogue for studying the relative effects of IGF-I through the type 1 receptor and IGF binding proteins.


Fact sheets

Human [Leu60] IGF-I specifications

Human [Leu60] IGF-I SDS

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