- 100 µl
- Product code
Human ProIGF-II E (78-88) antiserum was prepared by immunising rabbits with an 11 amino acid peptide derived from the E domain of human IGF-II E linked to diphtheria toxoid. The sequence corresponds to IGF-II E77-88and as a consequence, the antiserum recognises full length IGF-II E and both IGF-II E variants (IGF-II E1-88 andIGF-II E1-104)derived from processing of the human igf-2 gene and following proteolytic cleavage. It does not recognise mature IGF-II or IGF-I. Sequence analysis suggests it is likely to recognise IGF-II E proteins in non-human primates, dog, guinea-pig, pig and a number of other species.